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        1. 當前位置 首頁 科研隊伍

          中科院青促會會員

          馮菡  博士 副研究員  

          中國科學院青年創新促進會會員

          研究方向:病原菌感染及宿主免疫應答

          電子郵件:qingfengpa@163.com

          電       話:

          通訊地址:北京市朝陽區大屯路15號(100101)

          英文版個人網頁:http://english.ibp.cas.cn/faculty/index_18316.html?json=http://www.salesdujour.com/sourcedb_ibp_cas/cn/ibpexport/EN_zkyqchhy/202005/t20200519_5582885.json

           

          簡       歷:

            2006.09 - 2011.06  吉林大學,學士

            2011.09 - 2016.06  中國科學院生物物理研究所,博士

            2016.07 - 2019.12  中國科學院生物物理研究所,助理研究員

            2020.01 - 至今        中國科學院生物物理研究所,副研究員

          獲獎及榮譽:

           

          社會任職:

           

          研究方向:

            利用結構生物學手段(X-ray 和冷凍電鏡)并結合生物化學及細胞生物學等手段,探索感染與免疫相關的生物學問題,包括病原體感染及宿主免疫應答兩個方面。

          承擔項目情況:

           

          代表論著:

          1. Feng Na#, Feng Han#, Wang Sheng, Avinash S. Punekar, Rudolf Ladenstein, Wang Da-Cheng, Zhang Qinghua*, Ding Jingjin* and Liu Wei*. Structures of heat shock factor trimers bound to DNA. iScience, 2021.9.24 :102951

          2. Feng Han#, Tian Huabin#, Wang Yong, Zhang Qixiang, Lin Ni, Liu Songqing, Yu Yang, Deng Hongyu*, Gao Pu*. Molecular mechanism underlying selective inhibition of mRNA nuclear export by herpesvirus protein ORF10. PNAS, 2020.10.27 117 (43) 26719-26727

          3. Zhu Yalan#; Gao Ang#; Zhan Yi; Wang Yong; Feng Han; Liu Songqing; A. Serganov* and Gao Pu*. Diverse Mechanisms of CRISPR-Cas9 Inhibition by Type IIC Anti-CRISPR Proteins. Molecular cell,2019.4.18 74(2): 296~309.

          4. Wang Yong#; Shi Miao; Feng Han; Zhu Yalan; Liu Songqing; Gao Ang*; Gao Pu*. Structural Insights into Non-canonical Ubiquitination Catalyzed by SidE. Cell, 2018.5.17 173(5): 1231~1243.

          5. Feng Han#; Liu Xuehui; Wang Sheng; Fleming Joy; Wang Da-Cheng*; LiuWei*. The mechanism of NDM-1-catalyzed carbapenem hydrolysis is distinct from that of penicillin or cephalosporin hydrolysis. Nature Communications, 2017.12.21 8(2242).

          6. Feng Han#; Ding Jingjin#; Zhu Deyu#; Liu Xuehui; Xu Xueyong; Zhang Ying; Zang Shanshan; Wang Da-Cheng*; Liu Wei*. Structural and Mechanistic Insights into NDM-1 Catalyzed Hydrolysis of Cephalosporins. Journal of the American Chemical Society, 2014.10.22 136(42): 14694~14697.

          7. Wang Yong#; Feng Han#; Zhu Yalan; Gao Pu(*).Structural insights into glutathione-mediated activation of the master regulator PrfA in Listeria monocytogenes. Protein & Cell, 2017.03.07 8: 308~312.

          8. Feng Han#; Wang Sheng#; Guo Ling; Punekar Avinash S.; Ladenstein Rudolf; Wang Da-Cheng*; Liu Wei*. MD simulation of high-resolution X-ray structures reveals post-translational modification dependent conformational changes in HSF-DNA interaction. Protein & Cell, 2016.12 7(12) : 916~920.

          9. Feng Han#; Liu Wei; Wang Da-Cheng*. Purification crystallization and X-ray diffraction analysis of the DNA-binding domain of human heat-shock factor 2. Acta Crystallographica Section F-Structural Biology Communications, 2016.4 72 : 294~299.

           

          (資料來源:馮涵副研究員,2021-12-29)

           

          公交上拨开少妇内裤挺进去

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