<address id="uqqsu"><pre id="uqqsu"><span id="uqqsu"></span></pre></address>

        <track id="uqqsu"></track>
        1. 當前位置 首頁 科研隊伍

          中科院青促會會員

          李穎峰  博士 副研究員  

          中國科學院青年創新促進會會員
          中科院生物物理所,生物大分子國家重點實驗室

          研究方向:表觀遺傳學

          電子郵件:liyingfeng@ibp.ac.cn

          電       話:010-64888213

          通訊地址:北京市朝陽區大屯路15號(100101)

          英文版個人網頁:http://english.ibp.cas.cn/faculty/index_18316.html?json=http://www.salesdujour.com/sourcedb_ibp_cas/cn/ibpexport/EN_zkyqchhy/202203/t20220322_6401944.json

           

          簡       歷:

            2006.09 – 2010.06  武漢大學生命科學學院,學士

            2010.09 – 2019.03  北京生命科學研究所/北京師范大學,博士

            2019.03 – 2021.11  中科院生物物理所,博士后

            2021.11 – 2022.01  中科院生物物理所,助理研究員

            2022.01 – 至今        中科院生物物理所,副研究員

          獲獎及榮譽:

           

          社會任職:

           

          研究方向:

            我們運用多學科前沿技術,致力于研究發育與疾病過程中的染色質調控機制:

            1. 哺乳動物早期胚胎染色質編程與重編程機制研究;

            2. 染色質調控蛋白突變的致病機制研究。

          承擔項目情況:

            1. 國家自然科學基金青年基金項目(32000559),2021-2023,負責人。

          代表論著:

          1. Zhang J#, Zhang Y#, You Q#, Huang C, Zhang T, Wang M, Zhang T, Yang X, Xiong J, Li Y, Liu C-P, Zhang Z, Xu R-M*, Zhu B*. Highly enriched BEND3 prevents the premature activation of bivalent genes during differentiation. Science. 2022, 375(6584): 1053-1058.

          2. Ming X, Zhu B*, Li Y*. Mitotic inheritance of DNA methylation: more than just copy and paste. Journal of Genetics and Genomics. 2021, 48(1): 1-13.

          3. Ming X#, Zhang Z#, Zou Z, Lv C, Dong Q, He Q, Yi Y, Li Y, Wang H, Zhu B*. Kinetics and mechanisms of mitotic inheritance of DNA methylation and their roles in aging-associated methylome deterioration. Cell Res. 2020, 30(11): 980-996.

          4. Du W, Dong Q, Zhang Z, Liu B, Zhou T, Xu R-m, Wang H, Zhu B, Li Y*. Stella protein facilitates DNA demethylation by disrupting the chromatin association of the RING finger-type E3 ubiquitin ligase UHRF1. J Biol Chem. 2019, 294(22): 8907-8917.

          5. Li Y#, Zhang Z#, Chen J#, Liu W, Lai W, Liu B, Li X, Liu L, Xu S, Dong Q, Wang M, Duan X, Tan J, Zheng Y, Zhang P, Fan G, Wong J, Xu G-L, Wang Z, Wang H, Gao S, Zhu B*. Stella safeguards the oocyte methylome by preventing de novo methylation mediated by DNMT1. Nature. 2018, 564(7734): 136-140.

          6. Li X, Shang E, Dong Q, Li Y, Zhang J, Xu S, Zhao Z, Shao W, Lv C, Zheng Y, Wang H, Lei X, Zhu B*, Zhang Z*. Small molecules capable of activating DNA methylation-repressed genes targeted by the p38 mitogen-activated protein kinase pathway. J Biol Chem. 2018, 293(19): 7423-7436.

          7. Huang C#, Zhang Z#, Xu M, Li Y, Li Z, Ma Y, Cai T, Zhu B*. H3.3-H4 Tetramer Splitting Events Feature Cell-Type Specific Enhancers. PLoS Genet. 2013, 9(6): e1003558.

          8. Wu H, Chen X, Xiong J, Li Y, Li H, Ding X, Liu S, Chen S, Gao S, Zhu B*. Histone methyltransferase G9a contributes to H3K27 methylation in vivo. Cell Res. 2011, 21(2): 365-367.

           

          (資料來源:李穎峰副研究員,2022-03-22)

           

          公交上拨开少妇内裤挺进去

                <address id="uqqsu"><pre id="uqqsu"><span id="uqqsu"></span></pre></address>

                <track id="uqqsu"></track>